Brown the Meats: In a skillet over medium heat, cook ground beef and sausage together until browned. Drain excess fat.
Melt the Cheese: Add cubed Velveeta (or blend with cream cheese) into the skillet. Stir until smooth and fully melted.
Season the Mixture: Stir in garlic powder, onion powder, cayenne, and black pepper. Mix well.
Prepare the Bread: Arrange cocktail rye slices on a baking sheet. Spoon the meat and cheese mixture onto each slice.
Bake : Place in a preheated oven at 350°F (175°C) for 10–12 minutes, until bubbly and edges of bread are crisp.
Serve Hot: Remove from oven and serve immediately for best flavor and texture.